Premium cosmetic-grade GHK-Cu powder — bulk manufacturer, OEM supplier, and wholesale distributor. ≥99% purity, ISO-certified, global shipping from Guangzhou, China.
GHK-Cu (glycyl-L-histidyl-L-lysine-copper), also known as Copper Tripeptide-1 or Blue Copper Peptide, is a naturally occurring copper complex with a potent affinity for skin repair and regeneration. It is one of the most extensively researched peptides in cosmetic science, with over 40 years of published studies supporting its efficacy in wound healing, collagen synthesis, and antioxidant defense.
GHK-Cu levels in human plasma decline with age — dropping from ~200 ng/mL at age 20 to ~80 ng/mL by age 60. Topical supplementation with blue copper peptide has been shown to help restore this age-related decline, promoting firmer, more resilient skin.
At YAKO Medical Aesthetics, we manufacture and supply high-purity GHK-Cu powder for cosmetic brands, contract manufacturers, and research laboratories worldwide. Our production facility in Guangzhou is ISO-certified, with every batch undergoing rigorous third-party testing for purity and potency.
| Product Name | GHK-Cu (Copper Tripeptide-1 / Blue Copper Peptide) |
|---|---|
| CAS Number | 89030-95-5 |
| Molecular Formula | C14H24N6O4Cu |
| Purity | ≥99% (HPLC) |
| Appearance | Blue lyophilized powder |
| Packaging | Vials (research-grade) / Bulk drums (cosmetic-grade, 100g–1kg) |
| Storage | 2–8°C, protected from light and moisture |
| Shelf Life | 24 months when stored as recommended |
| Minimum Order | 10g (research) / 100g (bulk cosmetic) |
GHK-Cu stimulates collagen Type I, III, and IV production, as well as elastin and proteoglycans — the core structural proteins of healthy skin. Effect observed at concentrations as low as 0.01 mM in dermal fibroblasts.
Accelerates wound contraction and re-epithelialization. GHK-Cu upregulates MMP-2 and TIMP-1/2, balancing tissue remodeling during the healing process. Used in post-procedure recovery formulations.
Acts as a superoxide dismutase (SOD) mimetic, neutralizing free radicals that drive oxidative stress and premature aging. Protects DNA and lipids from UV-induced damage independent of direct UV absorption.
Suppresses pro-inflammatory cytokines including IL-6 and TGF-beta. Clinically relevant for sensitive skin, rosacea-prone skin, and post-procedure recovery protocols.
GHK-Cu has been shown to stimulate hair follicle proliferation and reduce apoptosis in dermal papilla cells. Increasingly used in professional-grade hair restoration serums and scalp treatments.
With a molecular weight of ~340 Da, GHK-Cu readily penetrates the stratum corneum, making it an effective active ingredient in serums, creams, and mesotherapy formulations.
Our GHK-Cu powder is used by cosmetic brands and contract manufacturers in a wide range of finished products:
Water-based serums at 0.05–1% GHK-Cu, often combined with hyaluronic acid and matrixyl peptides.
Recovery formulations for use after microneedling, laser, and chemical peels at 0.1–0.5%.
Targeted delivery of GHK-Cu for periorbital firming and fine-line reduction.
Scalp formulations combining GHK-Cu with growth factors and vasodilators for hair retention.
Injectable-grade GHK-Cu for professional mesotherapy protocols targeting skin quality and laxity.
Copper peptide in body care formulations targeting skin elasticity on abdomen, arms, and thighs.
GMP-compliant production in our Guangzhou facility. Every batch is traceable.
HPLC purity analysis and heavy metal screening for every production lot.
Custom packaging, formulation support, and regulatory documentation for your brand.
Direct factory pricing with volume discounts for bulk cosmetic-grade GHK-Cu.
Reliable shipping to North America, Europe, Southeast Asia, and the Middle East.
Formulation guidance, solubility data, stability recommendations from our R&D team.
They are the same molecule. GHK-Cu is the scientific abbreviation (glycyl-L-histidyl-L-lysine-copper), while Copper Tripeptide-1 is the INCI name used on cosmetic ingredient labels.
0.05–0.2% in leave-on serums; 0.1–0.5% in post-procedure creams; up to 1% in professional mesotherapy preparations. Always conduct formulation-specific stability testing.
GHK-Cu is generally compatible with hyaluronic acid, matrixyl peptides, niacinamide, and most humectants. Avoid combining with strong acids (AHA/BHA at low pH) and high-concentration vitamin C (ascorbic acid) in the same formula without encapsulation.
Yes. We offer 10g research-grade samples for formulation testing and evaluation. Bulk orders start at 100g. Contact our sales team for sample requests and pricing.
Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and GMP compliance statement for every order. Custom regulatory support available for OEM partners.
Get a quote within 24 hours. Samples available for qualified buyers.
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